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Search Results for " bace1 in 2 "

7

Compounds

Cat No. Product Name Synonyms Targets
T10451 BACE1-IN-2 BACE
BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).
T61956 BACE1/2-IN-1
BACE1/2-IN-1 (compound 34) is an effective BACE1 and BACE2 inhibitor with IC50 of 0.01 and 0.0053 μM, respectively. BACE1/2-IN-1 has lower Pgp efflux ratio and improved passive permeability. The metabolic stability of BA...
T3394 Timosaponin BII Prototimosaponin A III Beta Amyloid , Others , BACE
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...
T4115 Auraptene 7-geranyloxycoumarin MMP , BACE
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...
T40393 OM99-2 OM99-2
OM99-2 is an eight-residue peptidomimetic with a high affinity for human brain memapsin 2, exhibiting a Ki value of 9.58 nM. This compound represents a significant advancement in the development of BACE1 inhibitors and h...
T40165 OM99-2 TFA OM99-2 TFA
OM99-2 TFA is an eight-residue peptidomimetic compound, functioning as a tight-binding inhibitor of human brain memapsin 2. It exhibits a high affinity for the target with a Ki value of 9.58 nM, making it a promising can...
T35975 6,9-Dichloro-1,2,3,4-tetrahydroacridine
6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids...
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